Anti-LRP5 Polyclonal Antibody

商品货号：	商品品牌：	规格	基本售价：	选择规格
K001578P-50ul	solarbio	50ul	960.00元
K001578P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-LRP5 Polyclonal Antibody
别名	BMND1;EVR1;EVR4;HBM;LR3;LRP-5; LRP7;OPPG;OPS;OPTA1;VBCH2
应用	WB IHC
稀释比例	WB 1:500-2000. IHC 1:50-200.
交叉反应	Human Mouse Rat
蛋白分子量	179kDa
Gene ID	4041
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human LRP5
性状	液体
Public Immunogen Range	Recombinant protein of human LRP5
Subcellular Locations	Endoplasmic reticulum Membrane Single-pass type I membrane protein
Swiss Prot	O75197
克隆类型	Polyclonal Antibody
背景资料	This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants.